Basics -- The Changing Epidemiology of Thyroid Cancer -- Histopathology, Immunohistochemistry, and Molecular Biology -- Familial Differentiated Carcinoma of the Thyroid -- The Diagnosis of Thyroid Cancer -- The Current Surgical Approach to Non-Medullary Thyroid Cancer -- Differentiated Thyroid Cancer -- Radioiodine Therapy for Thyroid Cancer -- 124I Positron Emission Tomographic Dosimetry and Positron Emission Tomography/Computed Tomography Imaging in Differentiated Thyroid Cancer -- External Beam Radiotherapy -- Thyroid Cancer: Treatment with Thyroid Hormone -- Treatment with Cytotoxic Drugs -- Redifferentiation Therapy of Thyroid Carcinomas with Retinoic Acid -- Follow-up of Patients with Well-Differentiated Thyroid Cancer -- Thyroglobulin as Specific Tumor Marker in Differentiated Thyroid Cancer -- Functional Imaging of Differentiated Thyroid Cancer -- Magnetic Resonance Imaging -- Thyroid Cancer in Chernobyl Children -- Medullary Thyroid Cancer -- Diagnosis of Medullary Thyroid Cancer -- Imaging in Medullary Thyroid Cancer -- Therapy for Medullary Thyroid Cancer -- Follow-up of Medullary Thyroid Cancer.

Thyroid Cancer describes all current diagnostic techniques, including FDG-PET and MRI. In recent years these modalities have documented hitherto hidden radioiodine-negative metastases, thus improving surgical therapy. The whole gamut of treatment, including surgery, radioiodine therapy, percutaneous radiation therapy and medical management, is covered. In some 10% of differentiated thyroid cancers, the well-known treatment tools of surgery and radioiodine therapy are not sufficient. New treatment modalities such as high-dose radioiodine therapy, redifferentiation therapy with retinoic acid and recombinant TSH are therefore highlighted. In a special section devoted to medullary thyroid cancer, new imaging procedures such as octreotide scintigraphy are described. The second edition includes two new chapters, on I-124 PET and dosimetry. Other chapters have been modified particularly in view of the new UICC classification, with special regard to the definition of T1 tumors.