Foundations -- Rationale of Intensity Modulated Radiation Therapy: A Clinician’s Point of View -- The Potential and Limitations of IMRT: A Physicist’s Point of View -- Imaging for IMRT -- Physical Optimization -- Practical IMRT Planning -- Dose Calculations for IMRT -- IMRT Delivery Techniques -- Biological Aspects of IMRT Planning and Delivery -- Image Guided Patient Setup -- QA-QC of IMRT: European Perspective -- QA-QC of IMRT: American Perspective -- Advanced Image-Guided and Biologically Guided Techniques -- Imaging Lymph Nodes Using CT and MRI, Imaging Cancer by PET -- PET and SPECT in IMRT: Future Prospects -- Magnetic Resonance Imaging for IMRT -- Molecular/Functional Image-guided Intensity Modulated Radiation Therapy -- Biological Optimization -- Advanced Imaging and Guidance System for Use in Intensity Modulated RT -- External Beam Adaptive Radiation Therapy (ART) on a Conventional Medical Accelerator -- Adaptive Radiation Therapy (ART) Strategies Using Helical Tomotherapy -- 4D CT Simulation -- 4D Treatment Planning -- “4D” IMRT Delivery -- Clinical -- IMRT for Paranasal Sinus and Nasal Cavity (Sino-Nasal) Tumors -- IMRT for Carcinomas of the Oropharynx and Oral Cavity -- IMRT for Carcinomas of the Nasopharynx -- Intensity Modulated Radiotherapy in Cancer of the Larynx -- Central Nervous System, Skull Base and Paraspinal Tumors -- IMRT Lung -- Breast IMRT -- IMRT for Malignancies of the Upper Abdomen and Retroperitoneum -- Prostate IMRT -- Intensity-modulated Radiation Therapy for Carcinomas of the Uterine Cervix and Endometrium -- Integration of IMRT and Brachytherapy -- High Precision and Unconventional Fractionation IMRT.

Intensity-modulated radiation therapy (IMRT), one of the most important developments in radiation oncology in the past 25 years, involves technology to deliver radiation to tumors in the right location, quantity and time. Unavoidable irradiation of surrounding normal tissues is distributed so as to preserve their function. The achievements and future directions in the field are grouped in the three sections of the book, each suitable for supporting a teaching course. Part 1 contains topical reviews of the basic principles of IMRT, part 2 describes advanced techniques such as image-guided and biologically based approaches, and part 3 focuses on investigation of IMRT to improve outcome at various cancer sites.