Clinical relevance of patch test reactions -- Historical Aspects -- Basic Features -- Mechanisms in Allergic Contact Dermatitis -- Molecular Aspects of Allergic Contact Dermatitis -- Mechanisms of Irritant Contact Dermatitis -- Immediate Contact Reactions -- Mechanisms of Phototoxic and Photoallergic Reactions -- Pathology -- Histopathological and Immunohistopathological Features of Irritant and Allergic Contact Dermatitis -- Ultrastructure of Irritant and Allergic Contact Dermatitis -- Individual Predisposition to Irritant and Allergic Contact Dermatitis -- Epidemiology -- Dermatotoxicology -- Skin Penetration -- Predictive Tests for Irritants and Allergens and Their Use in Quantitative Risk Assessment -- Allergic Contact Dermatitis in Humans — Experimental and Quantitative Aspects -- Clinical Features -- General Aspects -- Clinical Aspects of Irritant Contact Dermatitis -- Systemic Contact Dermatitis -- Phototoxic and Photoallergic Reactions -- Pigmented Contact Dermatitis and Chemical Depigmentation -- Hand Eczema -- Protein Contact Dermatitis -- Noneczematous Contact Reactions -- Diagnostic Tests -- Patch Testing -- Atopy Patch Testing with Aeroallergens and Food Proteins -- Patch Testing in Adverse Drug Reactions -- Allergens Exposure Assessment -- Skin Tests for Immediate Hypersensitivity -- Photopatch Testing -- Noninvasive Techniques for Quantification of Contact Dermatitis -- Allergic Contact Dermatitis Related to Specific Exposures -- Allergens from the Standard Series -- Cosmetics and Skin Care Products -- Allergens of Special Interest -- Metals Carola Lidén, Magnus Bruze, Torkil Menné -- Metalworking Fluids -- Plastic Materials -- Topical Drugs -- Dental Materials -- Clothing -- Shoes -- Occupational Contact Dermatitis -- Health Personnel -- Plants and Plant Products -- Pesticides -- Contact Allergy in Children -- Prevention and Therapy from Contact Dermatitis (with Special Reference to Occupational Dermatology) -- Legislation -- International Comparison of Legal Aspects of Worker Compensation for Occupational Contact Dermatitis -- Computers in the Management of Contact Dermatitis -- Contact Dermatitis Research Groups -- Patch Test Concentrations and Vehicles for Testing Contact Allergens -- Patch Testing with the Patients’Own Products -- Dictionary of Contact Allergens: Chemical Structures, Sources and References.

The fourth edition is an up-dated coverage of every conceivable aspect of the modern-day management of contact dermatitis. Both irritant and allergic contact dermatitis are covered fully and clearly, special emphasis being given to immunolgical mechanisms, molecular aspects of sensitizers, atypical clinical forms, reactions to drugs, occupational and environmental aspects. For optimizing the diagnostic approach a wide scale of information is provided. The editors and authors are all leading practitioners in the field. Their expertise has thus enabled the compilation of a comprehensive, yet approachable, updated text, supplemented by a large number of full color illustrations and tables. Core messages highlight the most important information and help the reader gain better understanding of the subject and greater competence in everyday practice. For teaching purposes a CD-ROM is included providing virtually all clinical pictures and the most pertinent diagrams and tables.