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Bone Marrow-Derived Progenitors [electronic resource] /edited by Katalin Kauser, Andreas-Michael Zeiher.

by Kauser, Katalin [editor.]; Zeiher, Andreas-Michael [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Handbook of Experimental Pharmacology: 180Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007.Description: IX, 289 p. online resource.ISBN: 9783540689768.Other title: With contributions by numerous experts.Subject(s): Medicine | Oncology | Immunology | Neurosciences | Toxicology | Biomedicine | Pharmacology/Toxicology | Neurosciences | Immunology | Cancer ResearchDDC classification: 615 Online resources: Click here to access online
Contents:
Basic Principles -- Mobilization of Bone Marrow-Derived Progenitors -- Role of Endothelial Nitric Oxide in Bone Marrow-Derived Progenitor Cell Mobilization -- Immune Plasticity of Bone Marrow-Derived Mesenchymal Stromal Cells -- Bone Marrow-Derived Cells: The Influence of Aging and Cellular Senescence -- Involvement of Marrow-Derived Endothelial Cells in Vascularization -- Therapeutic Implication and Clinical Experience -- Comparison of Intracardiac Cell Transplantation: Autologous Skeletal Myoblasts Versus Bone Marrow Cells -- Ischemic Tissue Repair by Autologous Bone Marrow-Derived Stem Cells: Scientific Basis and Preclinical Data -- Cell Therapy and Gene Therapy Using Endothelial Progenitor Cells for Vascular Regeneration -- Mesenchymal Stem Cells for Cardiac Regenerative Therapy -- Autotransplantation of Bone Marrow-Derived Stem Cells as a Therapy for Neurodegenerative Diseases -- Stem Cells as a Treatment for Chronic Liver Disease and Diabetes -- The Participation of Mesenchymal Stem Cells in Tumor Stroma Formation and Their Application as Targeted-Gene Delivery Vehicles.
In: Springer eBooksSummary: There is excitement generated almost daily about the possible uses of stem cells to treat human disease. The ability of stem cells to acquire different desired phenotype has opened the door for a new discipline: regenerative medicine. Much of the interest for this purpose is generated by embryonic stem cells, but their use is still controversial for moral reasons as well as scientifically. Less controversial and readily available are the adult bone marrow-derived progenitors including hematopoietic stem cells, endothelial progenitors and mesenchymal stem cells. The ambitious goal of this volume is to provide - in chapters written by accomplished scientists and experts in their field - a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells.
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Basic Principles -- Mobilization of Bone Marrow-Derived Progenitors -- Role of Endothelial Nitric Oxide in Bone Marrow-Derived Progenitor Cell Mobilization -- Immune Plasticity of Bone Marrow-Derived Mesenchymal Stromal Cells -- Bone Marrow-Derived Cells: The Influence of Aging and Cellular Senescence -- Involvement of Marrow-Derived Endothelial Cells in Vascularization -- Therapeutic Implication and Clinical Experience -- Comparison of Intracardiac Cell Transplantation: Autologous Skeletal Myoblasts Versus Bone Marrow Cells -- Ischemic Tissue Repair by Autologous Bone Marrow-Derived Stem Cells: Scientific Basis and Preclinical Data -- Cell Therapy and Gene Therapy Using Endothelial Progenitor Cells for Vascular Regeneration -- Mesenchymal Stem Cells for Cardiac Regenerative Therapy -- Autotransplantation of Bone Marrow-Derived Stem Cells as a Therapy for Neurodegenerative Diseases -- Stem Cells as a Treatment for Chronic Liver Disease and Diabetes -- The Participation of Mesenchymal Stem Cells in Tumor Stroma Formation and Their Application as Targeted-Gene Delivery Vehicles.

There is excitement generated almost daily about the possible uses of stem cells to treat human disease. The ability of stem cells to acquire different desired phenotype has opened the door for a new discipline: regenerative medicine. Much of the interest for this purpose is generated by embryonic stem cells, but their use is still controversial for moral reasons as well as scientifically. Less controversial and readily available are the adult bone marrow-derived progenitors including hematopoietic stem cells, endothelial progenitors and mesenchymal stem cells. The ambitious goal of this volume is to provide - in chapters written by accomplished scientists and experts in their field - a comprehensive overview of the currently available information related to the therapeutic utility of adult bone marrow-derived cells.

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