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Systems Biology and Computational Proteomics [electronic resource] :Joint RECOMB 2006 Satellite Workshops on Systems Biology and on Computational Proteomics, San Diego, CA, USA, December 1-3, 2006, Revised Selected Papers / edited by Trey Ideker, Vineet Bafna.

by Ideker, Trey [editor.]; Bafna, Vineet [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Lecture Notes in Computer Science: 4532Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2007.Description: IX, 131 p. Also available online. online resource.ISBN: 9783540730606.Subject(s): Computer science | Data structures (Computer science) | Computer software | Computational complexity | Database management | Bioinformatics | Biology -- Data processing | Computer Science | Algorithm Analysis and Problem Complexity | Discrete Mathematics in Computer Science | Data Structures | Database Management | Computational Biology/Bioinformatics | Computer Appl. in Life SciencesDDC classification: 005.1 Online resources: Click here to access online
Contents:
Not All Scale Free Networks Are Born Equal: The Role of the Seed Graph in PPI Network Emulation -- Probabilistic Paths for Protein Complex Inference -- Markov Additive Chains and Applications to Fragment Statistics for Peptide Mass Fingerprinting -- A Context-Specific Network of Protein-DNA and Protein-Protein Interactions Reveals New Regulatory Motifs in Human B Cells -- Identification and Evaluation of Functional Modules in Gene Co-expression Networks -- A Linear Discrete Dynamic System Model for Temporal Gene Interaction and Regulatory Network Influence in Response to Bioethanol Conversion Inhibitor HMF for Ethanologenic Yeast -- A Computational Approach for the Identification of Site-Specific Protein Glycosylations Through Ion-Trap Mass Spectrometry -- De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis -- Alignment of Mass Spectrometry Data by Clique Finding and Optimization.
In: Springer eBooksSummary: This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events - the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The 9 revised full papers presented were carefully reviewed and selected from around 50 submissions to both events. The papers of the Systems Biology meeting cover various aspects of systems biology, including integration of genome-wide microarray, proteomic, and metabolomic data, inference and comparison of biological networks, and model testing through design of experiments. The Computational Proteomics meeting focused on on computational mass spectrometry. The papers explore the use of this technology in various proteomic applications, such as protein identification and quantification in specific cellular environments, structural genomics, networks of protein interaction, and post-translational modifications.
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Not All Scale Free Networks Are Born Equal: The Role of the Seed Graph in PPI Network Emulation -- Probabilistic Paths for Protein Complex Inference -- Markov Additive Chains and Applications to Fragment Statistics for Peptide Mass Fingerprinting -- A Context-Specific Network of Protein-DNA and Protein-Protein Interactions Reveals New Regulatory Motifs in Human B Cells -- Identification and Evaluation of Functional Modules in Gene Co-expression Networks -- A Linear Discrete Dynamic System Model for Temporal Gene Interaction and Regulatory Network Influence in Response to Bioethanol Conversion Inhibitor HMF for Ethanologenic Yeast -- A Computational Approach for the Identification of Site-Specific Protein Glycosylations Through Ion-Trap Mass Spectrometry -- De Novo Signaling Pathway Predictions Based on Protein-Protein Interaction, Targeted Therapy and Protein Microarray Analysis -- Alignment of Mass Spectrometry Data by Clique Finding and Optimization.

This book constitutes the thoroughly refereed post-proceedings of two joint RECOMB 2006 satellite events - the Second Annual Workshop on Systems Biology, RSB 2006, and the First Biennial Workshop on Computational Proteomics, RCP 2006, held in San Diego, CA, USA in December 2006. The 9 revised full papers presented were carefully reviewed and selected from around 50 submissions to both events. The papers of the Systems Biology meeting cover various aspects of systems biology, including integration of genome-wide microarray, proteomic, and metabolomic data, inference and comparison of biological networks, and model testing through design of experiments. The Computational Proteomics meeting focused on on computational mass spectrometry. The papers explore the use of this technology in various proteomic applications, such as protein identification and quantification in specific cellular environments, structural genomics, networks of protein interaction, and post-translational modifications.

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