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Transporters as Targets for Drugs [electronic resource] /edited by Susan Napier, Matilda Bingham.

by Napier, Susan [editor.]; Bingham, Matilda [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Topics in Medicinal Chemistry: 4Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : 2009.Description: online resource.ISBN: 9783540879121.Other title: With contributions by numerous experts.Subject(s): Chemistry | Medicine | Toxicology | Chemistry, Organic | Biochemistry | Chemistry | Medicinal Chemistry | Pharmacology/Toxicology | Organic Chemistry | Molecular MedicineDDC classification: 615.19 Online resources: Click here to access online
Contents:
Overview: Transporters as Targets for Drug Discovery -- Membrane Transporters: Structure, Function and Targets for Drug Design -- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs -- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter -- The Design, Synthesis and Structure–Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors -- Molecular Imaging of Transporters with Positron Emission Tomography -- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ? -- Glycine Transporters and Their Inhibitors.
In: Springer eBooksSummary: M. Bingham • S. Napier: Overview: Transporters as Targets for Drug Discovery I. Sylte • A.W. Ravna • G. Sager • S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug Design G.A. Whitlock • M.D. Andrews • A.D. Brown • P.V Fish • A. Stobie • F. Wakehut: Design of Monoamine Reuptake Inhibitors – SSRIs, SNRIs and NRIs A. Hauck Newman • J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine’s Mechanism at the Dopamine Transporter Z. Chen • J. Yang • P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors G. Antoni • J. Sörensen • H. Hall: Molecular Imaging of Transporters with Positron Emission Tomography R. Bridges • S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xc R. Gilfillan • J. Kerr G. • Walker • G. Wishart: Glycine Transporters and Their Inhibitors
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Overview: Transporters as Targets for Drug Discovery -- Membrane Transporters: Structure, Function and Targets for Drug Design -- Design of Monoamine Reuptake Inhibitors: SSRIs, SNRIs and NRIs -- Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine's Mechanism at the Dopamine Transporter -- The Design, Synthesis and Structure–Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors -- Molecular Imaging of Transporters with Positron Emission Tomography -- Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System x c ? -- Glycine Transporters and Their Inhibitors.

M. Bingham • S. Napier: Overview: Transporters as Targets for Drug Discovery I. Sylte • A.W. Ravna • G. Sager • S.G. Dahl: Membrane Transporters: Structure, Function and Targets for Drug Design G.A. Whitlock • M.D. Andrews • A.D. Brown • P.V Fish • A. Stobie • F. Wakehut: Design of Monoamine Reuptake Inhibitors – SSRIs, SNRIs and NRIs A. Hauck Newman • J.L. Katz: Atypical Dopamine Uptake Inhibitors that Provide Clues About Cocaine’s Mechanism at the Dopamine Transporter Z. Chen • J. Yang • P. Skolnick: The Design, Synthesis and Structure-Activity Relationship of Mixed Serotonin, Norepinephrine and Dopamine Uptake Inhibitors G. Antoni • J. Sörensen • H. Hall: Molecular Imaging of Transporters with Positron Emission Tomography R. Bridges • S.A. Patel: Pharmacology of Glutamate Transport in the CNS: Substrates and Inhibitors of Excitatory Amino Acid Transporters (EAATs) and the Glutamate/Cystine Exchanger System xc R. Gilfillan • J. Kerr G. • Walker • G. Wishart: Glycine Transporters and Their Inhibitors

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