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Sepsis Management [electronic resource] :PIRO and MODS / edited by Jordi Rello, J. Lipman, Thiago Lisboa.

by Rello, Jordi [editor.]; Lipman, J [editor.]; Lisboa, Thiago [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookPublisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2012.Description: VI, 243p. 18 illus., 8 illus. in color. online resource.ISBN: 9783642035197.Subject(s): Medicine | Anesthesiology | Critical care medicine | Internal medicine | Emerging infectious diseases | Pneumology | Medicine & Public Health | Intensive / Critical Care Medicine | Infectious Diseases | Pneumology/Respiratory System | Anesthesiology | Internal MedicineDDC classification: 616.028 Online resources: Click here to access online In: Springer eBooksSummary: This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.
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This book is unique in approaching multiple organ dysfunction syndrome (MODS) from the perspective of its pathophysiological mechanism, and addressing aspects that are overlooked in most of the available literature. Eminent experts in the field from Europe and beyond offer new insights into risk stratification, severity assessment, and management of critically ill patients with sepsis. The principal focus is on recently developed concepts in infection management and in antibiotic use, bearing in mind that in these patients the pharmacokinetics of antibiotics are altered, affecting renal clearance and requiring dosage adjustments. The significance of the PIRO (predisposing factors, infection, response, organ dysfunction) model in the development of effective treatment strategies is emphasized. This book will be of interest and value to all who are involved in the treatment of, or research into, sepsis and MODS.

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