Environmental Epigenomics in Health and Disease [electronic resource] :Epigenetics and Disease Origins / edited by Randy L Jirtle, Frederick L. Tyson.
by Jirtle, Randy L [editor.]; Tyson, Frederick L [editor.]; SpringerLink (Online service).
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BookSeries: Epigenetics and Human Health: Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : 2013.Description: XV, 302 p. 41 illus., 34 illus. in color. online resource.ISBN: 9783642233807.Subject(s): Medicine | Oncology | Human genetics | Medical genetics | Biomedicine | Human Genetics | Cancer Research | Gene FunctionDDC classification: 611.01816 | 599.935 Online resources: Click here to access online
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Springer eBooksSummary: Exposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, cocaine, radiation, tobacco smoke, and xenoestrogens. Particular emphasis is placed on the consequences of environmental exposures during development on epigenetic reprogramming that influences adult disease pathogenesis. Health outcomes associated with these exposures include autoimmune disorders, neurodevelopmental disorders, and cancer. Importantly, dietary supplements and drugs can modify the epigenetic effects induced by these agents, thereby reducing their toxicological impact. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic processes and developmental programming.
| Item type | Current location | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|
| QH431 (Browse shelf) | Available | ||||
| Long Loan | MAIN LIBRARY | RB155-155.8 (Browse shelf) | Available |
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Exposure to environmental toxicants is associated with changes in DNA methylation and gene expression profiles that together can contribute to increased disease susceptibility. The chapters in this volume, Environmental Epigenomics in Health and Disease - Epigenetics and Disease Origins, address a wide range of environmental exposures, such as airborne particulates, cocaine, radiation, tobacco smoke, and xenoestrogens. Particular emphasis is placed on the consequences of environmental exposures during development on epigenetic reprogramming that influences adult disease pathogenesis. Health outcomes associated with these exposures include autoimmune disorders, neurodevelopmental disorders, and cancer. Importantly, dietary supplements and drugs can modify the epigenetic effects induced by these agents, thereby reducing their toxicological impact. The overall purpose of this volume and its companion, Environmental Epigenomics in Health and Disease - Epigenetics and Complex Diseases, is to give readers an overview of how environmental exposures during early development can influence disease formation by disrupting epigenetic processes and developmental programming.
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