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Epigenetic Regulation of Lymphocyte Development [electronic resource] /edited by Cornelis Murre.

by Murre, Cornelis [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Current Topics in Microbiology and Immunology: 356Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg, 2012.Description: X, 194 p. online resource.ISBN: 9783642241031.Subject(s): Medicine | Gene expression | Immunology | Biomedicine | Immunology | Gene ExpressionDDC classification: 616.079 Online resources: Click here to access online In: Springer eBooksSummary: Previous observations, generated by many in the field, have provided a first glimpse into the epigenetic mechanisms that underpin lymphocyte and myeloid development. We are only now beginning to merge the multitude of observations into a common framework. At the same time it has become more difficult for the individual mind to comprehend more than a tiny focused fraction of it. The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.
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Previous observations, generated by many in the field, have provided a first glimpse into the epigenetic mechanisms that underpin lymphocyte and myeloid development. We are only now beginning to merge the multitude of observations into a common framework. At the same time it has become more difficult for the individual mind to comprehend more than a tiny focused fraction of it. The studies described in this volume serve as a starting point to familiarize one self with the multifarious differences in epigenetic designs that orchestrate the progression of developing blood cells. They also may serve as a general paradigm for the mechanisms that underpin the control of eukaryotic gene expression.

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