RNA Metabolism in Trypanosomes [electronic resource] /edited by Albrecht Bindereif.
by Bindereif, Albrecht [editor.]; SpringerLink (Online service).
Material type:
BookSeries: Nucleic Acids and Molecular Biology: 28Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : 2012.Description: VI, 271 p. 27 illus., 22 illus. in color. online resource.ISBN: 9783642286872.Subject(s): Life sciences | Gene expression | Medical parasitology | Nucleic acids | Microbiology | Life Sciences | Nucleic Acid Chemistry | Eukaryotic Microbiology | Parasitology | Gene ExpressionDDC classification: 572.84 Online resources: Click here to access online | Item type | Current location | Call number | Status | Date due | Barcode |
|---|---|---|---|---|---|
| MAIN LIBRARY | QD433-436 (Browse shelf) | Available |
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| QP82-82.2 Living in a Seasonal World | GE1-350 Solid Waste Management | QC174.7-175.36 Statistical Physics | QD433-436 RNA Metabolism in Trypanosomes | TA329-348 Risk Assessment and Management in the Networked Economy | TA1-2040 Advances in Intelligent Signal Processing and Data Mining | RC254-282 Primary Liver Cancer |
RNA Polymerases and Transcription Factors of Trypanosomes -- SL RNA biogenesis in kinetoplastids: a long and winding road -- Pre-mRNA splicing in Trypanosoma brucei: factors, mechanisms, and regulation -- mRNA turnover in trypanosomes -- tRNA biogenesis and processing -- rRNA biogenesis in trypanosomes -- RNA Editing in African Trypanosomes – a User’s Guide -- The RNA Interference Pathway in Trypanosoma brucei -- Translation in trypanosomatids -- Mitochondrial translation in trypanosomatids -- RNA-Seq analysis of the transcriptome of Trypanosoma brucei.
Trypanosomes are unicellular protozoa of ancient evolutionary origin that are responsible for several tropical diseases, such as African sleeping sickness. Over the last few decades, research in trypanosome biology has revealed many unique and fascinating features, many of which have helped to establish new paradigms in other biological systems. This applies in particular to studies in gene expression and regulation, which benefit enormously from the trypanosome genome projects and from the new genome-wide approaches recently introduced in trypanosome research. This volume covers the most important aspects of biosynthesis, processing, and functions of RNA in trypanosomes, ranging from transcription to RNA editing, mRNA splicing/translation/turnover, processing of transfer and ribosomal RNA, RNA interference, and current transcriptome-wide analyses. Recent progress in RNA-focused research in trypanosomatids promises to yield novel insights into trypanosome-specific features, as well as to reveal in the process new potential therapeutic strategies for combating these parasitic diseases.
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