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Protein-Protein Interactions [electronic resource] /edited by Michael D. Wendt.

by Wendt, Michael D [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Topics in Medicinal Chemistry: 8Publisher: Berlin, Heidelberg : Springer Berlin Heidelberg : 2012.Description: XVIII, 261 p. 175 illus., 39 illus. in color. online resource.ISBN: 9783642289651.Subject(s): Chemistry | Chemistry | Chemistry/Food Science, generalDDC classification: 540 Online resources: Click here to access online
Contents:
Protein-Protein Interactions as Drug Targets -- Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics -- The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer -- Protein-Protein Interaction Targets to Inhibit HIV-1 Infection -- Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion – a Focus on Respiratory Syncytial Virus -- Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces -- The Discovery of Navitoclax, a Bcl-2 Family Inhibitor.
In: Springer eBooksSummary: Michael D. Wendt Protein-Protein Interactions as Drug Targets Shaomeng Wang , Yujun Zhao , Denzil Bernard , Angelo Aguilar , Sanjeev Kumar Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics Kurt Deshayes , Jeremy Murray , Domagoj Vucic The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer John F. Kadow , David R. Langley , Nicholas A. Meanwell , Michael A. Walker , Kap-Sun Yeung , Richard Pracitto Protein-Protein Interaction Targets to Inhibit HIV-1 Infection Nicholas A. Meanwell , David R. Langley Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion – a Focus on Respiratory Syncytial Virus Andrew B. Mahon , Stephen E. Miller , Stephen T. Joy , Paramjit S. Arora Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces Michael D. Wendt The Discovery of Navitoclax, a Bcl-2 Family Inhibitor
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Protein-Protein Interactions as Drug Targets -- Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics -- The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer -- Protein-Protein Interaction Targets to Inhibit HIV-1 Infection -- Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion – a Focus on Respiratory Syncytial Virus -- Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces -- The Discovery of Navitoclax, a Bcl-2 Family Inhibitor.

Michael D. Wendt Protein-Protein Interactions as Drug Targets Shaomeng Wang , Yujun Zhao , Denzil Bernard , Angelo Aguilar , Sanjeev Kumar Targeting the MDM2-p53 Protein-Protein Interaction for New Cancer Therapeutics Kurt Deshayes , Jeremy Murray , Domagoj Vucic The Development of Small-Molecule IAP Antagonists for the Treatment of Cancer John F. Kadow , David R. Langley , Nicholas A. Meanwell , Michael A. Walker , Kap-Sun Yeung , Richard Pracitto Protein-Protein Interaction Targets to Inhibit HIV-1 Infection Nicholas A. Meanwell , David R. Langley Inhibitors of Protein-Protein Interactions in Paramyxovirus Fusion – a Focus on Respiratory Syncytial Virus Andrew B. Mahon , Stephen E. Miller , Stephen T. Joy , Paramjit S. Arora Rational Design Strategies for Developing Synthetic Inhibitors of Helical Protein Interfaces Michael D. Wendt The Discovery of Navitoclax, a Bcl-2 Family Inhibitor

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