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Molecular Mechanisms of Basal Cell and Squamous Cell Carcinomas [electronic resource] /by Jörg Reichrath.

by Reichrath, Jörg [author.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Medical Intelligence Unit: Publisher: Boston, MA : Springer US, 2006.Description: XV, 137 p. online resource.ISBN: 9780387350981.Subject(s): Medicine | Oncology | Pathology | Biomedicine | Cancer Research | Oncology | PathologyDDC classification: 614.5999 Online resources: Click here to access online
Contents:
The Epidemiology of Basal Cell and Squamous Cell Carcinoma -- Histology of Epithelial Skin Tumors -- UV Damage and DNA Repair in Basal Cell and Squamous Cell Carcinomas -- Papillomavirus Infections and Cancerogenesis of Squamous Cell and Basal Cell Carcinomas -- The Immune System and Nonmelanoma Skin Cancers -- Cytogenetics of Basal Cell Carcinoma and Squamous Cell Carcinomas -- The Hedgehog Signaling Pathway and Epithelial Skin Cancer -- p53 Protein and Nonmelanoma Skin Cancer -- TGF-? Pathway and Cancerogenesis of Epithelial Skin Tumors -- PDGF Pathways and Growth of Basal Cell and Squamous Cell Carcinomas -- Apoptosis and Cancerogenesis of Basal Cell and Squamous Cell Carcinoma -- The Role of Telomerase for Cancerogenesis of Basal Cell and Squamous Cell Carcinomas.
In: Springer eBooksSummary: This book provides a comprehensive, highly readable overview of our current knowledge of the molecular pathology of basal cell and squamous cell carcinomas. The chapters present the newest findings in epidemiology, photocarcinogenesis, genetics, immunology and molecular pathology of these epithelial skin tumours. Topics include the importance of the hedgehog/patched/smoothened/GLI, p53, PDGF, or TGF-b signalling pathways as well as the relevance of papilloma virus infections, apoptosis, DNA-repair and telomerase.
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The Epidemiology of Basal Cell and Squamous Cell Carcinoma -- Histology of Epithelial Skin Tumors -- UV Damage and DNA Repair in Basal Cell and Squamous Cell Carcinomas -- Papillomavirus Infections and Cancerogenesis of Squamous Cell and Basal Cell Carcinomas -- The Immune System and Nonmelanoma Skin Cancers -- Cytogenetics of Basal Cell Carcinoma and Squamous Cell Carcinomas -- The Hedgehog Signaling Pathway and Epithelial Skin Cancer -- p53 Protein and Nonmelanoma Skin Cancer -- TGF-? Pathway and Cancerogenesis of Epithelial Skin Tumors -- PDGF Pathways and Growth of Basal Cell and Squamous Cell Carcinomas -- Apoptosis and Cancerogenesis of Basal Cell and Squamous Cell Carcinoma -- The Role of Telomerase for Cancerogenesis of Basal Cell and Squamous Cell Carcinomas.

This book provides a comprehensive, highly readable overview of our current knowledge of the molecular pathology of basal cell and squamous cell carcinomas. The chapters present the newest findings in epidemiology, photocarcinogenesis, genetics, immunology and molecular pathology of these epithelial skin tumours. Topics include the importance of the hedgehog/patched/smoothened/GLI, p53, PDGF, or TGF-b signalling pathways as well as the relevance of papilloma virus infections, apoptosis, DNA-repair and telomerase.

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