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Innovative Endocrinology of Cancer [electronic resource] /edited by Lev M. Berstein, Richard J. Santen.

by Berstein, Lev M [editor.]; Santen, Richard J [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Advances in Experimental Medicine and Biology: 630Publisher: New York, NY : Springer New York, 2008.Description: online resource.ISBN: 9780387788180.Subject(s): Medicine | Oncology | Biomedicine | Cancer ResearchDDC classification: 614.5999 Online resources: Click here to access online
Contents:
Mechanisms of Hormone Carcinogenesis: -- Adaptation to Estradiol Deprivation Causes Up-Regulation of Growth Factor Pathways and Hypersensitivity to Estradiol in Breast Cancer Cells -- Role of Endocrine-Genotoxic Switchings in Cancer and Other Human Diseases: -- Breast Development, Hormones and Cancer -- Epidemiology of Hormone-Associated Cancers as a Reflection of Age -- Obesity and Diabetes Epidemics: -- Progesterone Receptor Action: -- Aromatase Expression in Women’s Cancers -- Proteomics of Cancer of Hormone-Dependent Tissues -- Endogenous Hormone Levels and Risk of Breast, Endometrial and Ovarian Cancers: -- Hormonal Heterogeneity of Endometrial Cancer -- Cell Cycle Machinery: -- Selective Estrogen Modulators as an Anticancer Tool: -- Pharmacogenomics of Endocrine Therapy in Breast Cancer -- Prevention of Breast Cancer Using SERMs -- General Conclusion.
In: Springer eBooksSummary: This volume is devoted to the new developments in such topics as mechanisms of hormonal carcinogenesis, epidemiology and risk factors, hormone production by tumor tissue and hormonal sensitivity of the latter, genesis, dichotomy and endocrinology of cancer in females, pharmacogenomics and proteomics in oncoendocrinology, biological core of hormonal and antihormonal therapy of cancer and its prevention.
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Mechanisms of Hormone Carcinogenesis: -- Adaptation to Estradiol Deprivation Causes Up-Regulation of Growth Factor Pathways and Hypersensitivity to Estradiol in Breast Cancer Cells -- Role of Endocrine-Genotoxic Switchings in Cancer and Other Human Diseases: -- Breast Development, Hormones and Cancer -- Epidemiology of Hormone-Associated Cancers as a Reflection of Age -- Obesity and Diabetes Epidemics: -- Progesterone Receptor Action: -- Aromatase Expression in Women’s Cancers -- Proteomics of Cancer of Hormone-Dependent Tissues -- Endogenous Hormone Levels and Risk of Breast, Endometrial and Ovarian Cancers: -- Hormonal Heterogeneity of Endometrial Cancer -- Cell Cycle Machinery: -- Selective Estrogen Modulators as an Anticancer Tool: -- Pharmacogenomics of Endocrine Therapy in Breast Cancer -- Prevention of Breast Cancer Using SERMs -- General Conclusion.

This volume is devoted to the new developments in such topics as mechanisms of hormonal carcinogenesis, epidemiology and risk factors, hormone production by tumor tissue and hormonal sensitivity of the latter, genesis, dichotomy and endocrinology of cancer in females, pharmacogenomics and proteomics in oncoendocrinology, biological core of hormonal and antihormonal therapy of cancer and its prevention.

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