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Human Cell Transformation [electronic resource] :Role of Stem Cells and the Microenvironment / edited by Johng S. Rhim, Richard Kremer.

by Rhim, Johng S [editor.]; Kremer, Richard [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Advances in Experimental Medicine and Biology: 720Publisher: New York, NY : Springer New York : 2012.Description: XXII, 224p. 62 illus., 46 illus. in color. online resource.ISBN: 9781461402541.Subject(s): Life sciences | Cytology | Stem cells | Life Sciences | Cell Biology | Stem CellsDDC classification: 571.6 Online resources: Click here to access online
Contents:
Nuclear Barrier Hypothesis of Aging as Mechanism for Tradeoff Growth to Survival -- Establishment of Cell Lines from the Human Middle and Inner Ear Epithelial Cells -- Cellular Systems for Studying Human Oral Squamous Cell Carcinomas -- Heterotopic Ossification Following Musculoskeletal Trauma: Modeling Stem and Progenitor Cells in Their Microenvironment -- Comparative Proteomic Analysis of Mesenchymal Stem Cells Derived from Human Bone Marrow, Umbilical Cord, and Placenta: Implication in the Migration -- Novel Human Prostate Epithelial Cell Culture Models for the Study of Carcinogenesis and of Normal Stem Cells and Cancer Stem Cells -- Prostate Tumor Cell Plasticity: A Consequence of the Microenvironment -- Role of Epigenetics in Cancer Initiation and Progression -- Cancer Stem Cells, Models of Study and Implications of Therapy Resistance Mechanisms -- The Role of the Basal Stem Cell of the Human Breast in Normal Development and Cancer -- Breast Cancer Subtypes: Two Decades of Journey from Cell Culture to Patients -- Parathyroid Hormone Related Protein (PTHrP) in Tumor Progression -- Mechanism of Radiation Carcinogenesis: Role of the TGFBI Gene and The Inflammatory Signalling Cascade -- Histone Deacetylase Inhibitors: Anti-Neoplastic Agent and Radiation Modulator -- Human Fibroblasts for Large-Scale “Omics” Investigations of ATM Gene Function -- Malignant Transformation of Human Skin Fibroblasts by Two Alternative Pathways -- A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified By Our In Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-Tumor Agent.
In: Springer eBooksSummary: No back cover text
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Nuclear Barrier Hypothesis of Aging as Mechanism for Tradeoff Growth to Survival -- Establishment of Cell Lines from the Human Middle and Inner Ear Epithelial Cells -- Cellular Systems for Studying Human Oral Squamous Cell Carcinomas -- Heterotopic Ossification Following Musculoskeletal Trauma: Modeling Stem and Progenitor Cells in Their Microenvironment -- Comparative Proteomic Analysis of Mesenchymal Stem Cells Derived from Human Bone Marrow, Umbilical Cord, and Placenta: Implication in the Migration -- Novel Human Prostate Epithelial Cell Culture Models for the Study of Carcinogenesis and of Normal Stem Cells and Cancer Stem Cells -- Prostate Tumor Cell Plasticity: A Consequence of the Microenvironment -- Role of Epigenetics in Cancer Initiation and Progression -- Cancer Stem Cells, Models of Study and Implications of Therapy Resistance Mechanisms -- The Role of the Basal Stem Cell of the Human Breast in Normal Development and Cancer -- Breast Cancer Subtypes: Two Decades of Journey from Cell Culture to Patients -- Parathyroid Hormone Related Protein (PTHrP) in Tumor Progression -- Mechanism of Radiation Carcinogenesis: Role of the TGFBI Gene and The Inflammatory Signalling Cascade -- Histone Deacetylase Inhibitors: Anti-Neoplastic Agent and Radiation Modulator -- Human Fibroblasts for Large-Scale “Omics” Investigations of ATM Gene Function -- Malignant Transformation of Human Skin Fibroblasts by Two Alternative Pathways -- A Novel Tumor Suppressor, REIC/Dkk-3 Gene Identified By Our In Vitro Transformation Model of Normal Human Fibroblasts Works as a Potent Therapeutic Anti-Tumor Agent.

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