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Retinal Degenerations [electronic resource] :Biology, Diagnostics, and Therapeutics / edited by Joyce Tombran-Tink, Colin J. Barnstable.

by Tombran-Tink, Joyce [editor.]; Barnstable, Colin J [editor.]; SpringerLink (Online service).
Material type: materialTypeLabelBookSeries: Ophthalmology Research: Publisher: Totowa, NJ : Humana Press, 2007.Description: XIX, 466 p. With CD-ROM. online resource.ISBN: 9781597451864.Subject(s): Medicine | Neurosciences | Ophthalmology | Cytology | Medicine & Public Health | Ophthalmology | Neurosciences | Cell BiologyDDC classification: 617.7 Online resources: Click here to access online
Contents:
Living with Retinal Degeneration -- Coping With Retinal Degeneration -- Degenerative Diseases of the Retina -- Epidemiology of Age-Related Macular Degeneration Early in the 21st Century -- Leber Congenital Amaurosis -- Macular Degeneration -- Stargardt Disease -- X-Linked Juvenile Retinoschisis -- Retinal Degeneration in Usher Syndrome -- Mouse Models of RP -- Mechanisms Underlying Retinal Degenerations -- The Impact of Diabetes on Neuronal, Glial, and Vascular Cells of the Retina -- Statins and Age-Related Maculopathy -- The Role of Drusen in Macular Degeneration and New Methods of Quantification -- RPE Lipofuscin -- Genetic Modifiers That Affect Phenotypic Expression of Retinal Diseases -- X-Linked Retinal Dystrophies and Microtubular Functions Within the Retina -- Synaptic Remodeling in Retinal Degeneration -- Developing Therapeutic Strategies for Retinal Degenerative Diseases -- On The Suppression of Photoreceptor Cell Death in Retinitis Pigmentosa -- Cell-Based Therapies to Restrict the Progress of Photoreceptor Degeneration -- Current Status of IPE Transplantation and Its Potential as a Cell-Based Therapy for Age-Related Macular Degeneration and Retinal Dystrophies -- Recent Results in Retinal Transplantation Give Hope for Restoring Vision -- Stem Cells and Retinal Transplantation -- Application of Encapsulated Cell Technology for Retinal Degenerative Diseases -- Effective Treatment for the Canine RPE65 Null Mutation, a Hereditary Retinal Dystrophy Comparable to Human Leber’s Congenital Amaurosis -- Neuroprotective Factors and Retinal Degenerations -- Carbonic Anhydrase Inhibitors as a Possible Therapy for RP17, an Autosomal Dominant Retinitis Pigmentosa Associated With the R14W Mutation, Apoptosis, and the Unfolded Protein Response -- Macular Degeneration—An Addendum.
In: Springer eBooksSummary: This book focuses on what we currently know about the environment, genetics and mechanisms that lead to retinal degenerations, new diagnostics, and innovative therapeutic modalities to preserve vision.
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Living with Retinal Degeneration -- Coping With Retinal Degeneration -- Degenerative Diseases of the Retina -- Epidemiology of Age-Related Macular Degeneration Early in the 21st Century -- Leber Congenital Amaurosis -- Macular Degeneration -- Stargardt Disease -- X-Linked Juvenile Retinoschisis -- Retinal Degeneration in Usher Syndrome -- Mouse Models of RP -- Mechanisms Underlying Retinal Degenerations -- The Impact of Diabetes on Neuronal, Glial, and Vascular Cells of the Retina -- Statins and Age-Related Maculopathy -- The Role of Drusen in Macular Degeneration and New Methods of Quantification -- RPE Lipofuscin -- Genetic Modifiers That Affect Phenotypic Expression of Retinal Diseases -- X-Linked Retinal Dystrophies and Microtubular Functions Within the Retina -- Synaptic Remodeling in Retinal Degeneration -- Developing Therapeutic Strategies for Retinal Degenerative Diseases -- On The Suppression of Photoreceptor Cell Death in Retinitis Pigmentosa -- Cell-Based Therapies to Restrict the Progress of Photoreceptor Degeneration -- Current Status of IPE Transplantation and Its Potential as a Cell-Based Therapy for Age-Related Macular Degeneration and Retinal Dystrophies -- Recent Results in Retinal Transplantation Give Hope for Restoring Vision -- Stem Cells and Retinal Transplantation -- Application of Encapsulated Cell Technology for Retinal Degenerative Diseases -- Effective Treatment for the Canine RPE65 Null Mutation, a Hereditary Retinal Dystrophy Comparable to Human Leber’s Congenital Amaurosis -- Neuroprotective Factors and Retinal Degenerations -- Carbonic Anhydrase Inhibitors as a Possible Therapy for RP17, an Autosomal Dominant Retinitis Pigmentosa Associated With the R14W Mutation, Apoptosis, and the Unfolded Protein Response -- Macular Degeneration—An Addendum.

This book focuses on what we currently know about the environment, genetics and mechanisms that lead to retinal degenerations, new diagnostics, and innovative therapeutic modalities to preserve vision.

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