I: Neuroendocrine Control of Puberty -- 1 Control Puberty in Rodents: Special Focus on the Female -- 2 Control of Puberty in Non-Human Primates -- 3 Control of Puberty in Humans -- 4 Genetic Regulation of the Variation in Pubertal Timing -- II: Secular Trends and the Onset of Puberty -- 5 Puberty Is Starting Earlier in the 21st Century -- 6 BMI and the Onset of Puberty -- 7 Puberty Timing Remains Unchanged -- III: Isolated Breast Development -- 8 Premature Thelarche -- 9 Gynecomastia: Epidemiology, Pathophysiology, and Management -- IV: Adrenal Abnormalities and Puberty -- 10 Premature Adrenarche: Harbingers and Consequences -- 11 Pubertal Consequences of Being Born Small for Gestational Age -- 12 Congenital Adrenal Hyperplasia -- 13 Polycystic Ovary Syndrome in the Peripubertal Period -- 14 Psychological and Social Problems in Children With Premature Adrenarche and Precocious Puberty -- V: Gonadotropin-Dependent Precocious Puberty -- 15 Etiology of Gonadotropin-Dependent Precocious Puberty -- 16 Treatment of Gonadotropin Dependent Precocious Puberty -- VI: Gonadotropin-Independent Precocious Puberty -- 17 McCune—Albright Syndrome: Pathophysiology, Diagnosis, and Management -- 18 Familial Male-Limited Precocious Puberty -- 19 Gonadal and Adrenal Tumors -- VII: Environmental Effects on Puberty -- 20 The Role of Endocrine Disruptors in Pubertal Development -- 21 Precocious Puberty in Internationally Adopted Girls.

When Puberity is Precocious: Scientific and Clinical Aspects provides a unique continuum of expertise, looking at puberty from anthropologic, epidemiologic, clinical, and molecular perspectives. The volume addresses broad pubertal changes in the general population while at the same time providing in depth information about specific disorders of puberty and the latest management changes. The text is divided into seven parts. The first is an in-depth investigation into neuroendocrine control of puberty, the second looks at secular trends and the onset of puberty, and the third provides an examination into isolated breast development. The fourth section covers adrenal abnormalities and puberty, the next two sections include chapters on gonadotropin’s effects, and the final section is a looks at environmental effects on puberty. Comprehensive and timely, When Puberity is Precocious: Scientific and Clinical Aspects will become an essential reference for endocrinologists and internists with an interest in precocious puberty.